Wei S.-H.MING-CHIH HOYEN-HSUAN NIDONG-TSAMN LINPO-HUANG LEE2020-12-282020-12-2820070929-6646https://www.scopus.com/inward/record.uri?eid=2-s2.0-34248651552&doi=10.1016%2fS0929-6646%2809%2960261-8&partnerID=40&md5=d3138788f6ba36ffd4ddbc55b36324cdhttps://scholars.lib.ntu.edu.tw/handle/123456789/534214Immune thrombocytopenic purpura (ITP) is a rare complication after liver transplantation. Infection with cytomegalovirus (CMV) is a frequent complication of organ transplantation and may induce autoimmune diseases, such as ITP. We report a case of ITP after primary CMV infection in a 3-year-old boy recipient of living-related orthotopic liver transplantation (OLT). The ITP developed 2 years after OLT in this patient who had received tacrolimus as an immunosuppressive agent, with nadir platelet counts of 5000/mm3 in 2 weeks. The patient was treated with two courses of intravenous gamma globulin (1 g/kg/day for 2 days) and subsequent oral prednisolone (1.3 mg/kg/day for 2 weeks). He recovered from thrombocytopenia 4 weeks later. An inadequate immunosuppression, as evident by the low serum tacrolimus level (5.8 ng/ mL before the episode of ITP) in this patient, may allow the development of ITP after CMV infection. ? 2007 Elsevier & Formosan Medical Association.[SDGs]SDG3immunoglobulin; prednisolone; steroid; tacrolimus; antibody blood level; article; blood examination; case report; child; cytomegalovirus infection; drug blood level; graft rejection; human; liver transplantation; living donor; male; orthotopic transplantation; repeated drug dose; serology; thrombocyte count; thrombocytopenia; thrombocytopenic purpura; treatment duration; treatment outcomejournal article10.1016/S0929-6646(09)60261-8174756122-s2.0-34248651552