ATMIN Suppresses Metastasis by Altering the WNT-Signaling Pathway via PARP1 in MSI-High Colorectal Cancer

Li, Yue-JuYue-JuLiYang, Cheng-NingCheng-NingYangYEN-PING KUOLai, Wei-TingWei-TingLaiWu, Tai-ShengTai-ShengWuBEEN-REN LIN2021-12-012021-12-012021-1210689265https://scholars.lib.ntu.edu.tw/handle/123456789/589078Constant DNA damage occurs in cells, and the cells are programmed to respond constitutively. This study explored the roles of ataxia-telangiectasia mutated interactor (ATMIN), one of the impaired pathways involving the DNA damage response (DDR) in mismatch repair-deficient [microsatellite instability (MSI)-high] colorectal carcinoma (CRC).en[SDGs]SDG3ataxia telangiectasia mutated interactor; beta catenin; messenger RNA; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1; olaparib; protein; transcription factor 4; unclassified drug; ATMIN protein, human; nicotinamide adenine dATMIN Suppresses Metastasis by Altering the WNT-Signaling Pathway via PARP1 in MSI-High Colorectal Cancerjournal article10.1245/s10434-021-10322-5341481372-s2.0-85108257343https://scholars.lib.ntu.edu.tw/handle/123456789/569119