Water extract of Armillaria mellea (Vahl) P. Kumm. Alleviates the depression-like behaviors in acute- and chronic mild stress-induced rodent models via anti-inflammatory action

Lin, Yu-EnYu-EnLinWang, Hsiang-LanHsiang-LanWangKUAN-HUNG LUHuang, Yun-JuYun-JuHuangPanyod, SuraphanSuraphanPanyodLiu, Wei-TingWei-TingLiuYang, Shu-HuiShu-HuiYangChen, Mei-HsingMei-HsingChenLu, Yun-ShenYun-ShenLuLEE-YAN SHEEN2021-05-062021-05-062021-01-3003788741https://scholars.lib.ntu.edu.tw/handle/123456789/559840Armillaria mellea (Vahl) P. Kumm. (AM) is an edible mushroom that has been reported as treatment for several neurological disorders, such as dizziness and epilepsy in Asia. Importantly, AM shares a symbiotic relationship with Gastrodia elata Blume (GE), a medicinal herb with antidepressant-like properties. Researchers believe that AM may possess pharmacological properties similar to GE due to their symbiosis, however, few studies have investigated the pharmacological effect of AM.enArmillaria mellea (Vahl) P. Kumm.; Depression; Inflammation; Microglia; Unpredictable chronic mild stressWater extract of Armillaria mellea (Vahl) P. Kumm. Alleviates the depression-like behaviors in acute- and chronic mild stress-induced rodent models via anti-inflammatory actionjournal article10.1016/j.jep.2020.113395329567572-s2.0-85091224862https://api.elsevier.com/content/abstract/scopus_id/85091224862