放射線科YEN, RUOH-FANGRUOH-FANGYEN2009-01-162018-07-122009-01-162018-07-122002http://ntur.lib.ntu.edu.tw//handle/246246/96959The aim of this study was to evaluate practice usefulness of whole body positron emission tomography (PET) with 18F- fluoro-2-deoxyglucose (FDG) to detect recurrent ovarian cancer based on asymptomatically elevated tumor marker (CA- 125) serum levels. Whole-body FDG-PET was performed in 28 patients with suspected recurrent ovarian cancers and asymptomatically increased serum levels of tumor marker (CA- 125 antigen) but negative or equivocal other imaging modality results. All of these 28 asymptomatic patients had serum levels of CA-125 antigen >35 U/ml. The final diagnosis of recurrent ovarian cancer was established by operation/ biopsy histopathological findings or clinical follow-up longer than 1 year by additional morphologic imaging techniques. Among the 28 patients, the final diagnoses of recurrent ovarian cancers and benign lesions were established in 20 and 8 patients, respectively. FDG-PET accurately diagnosed recurrent ovarian cancers in 19 patients and benign lesions in 7 patients. When asymptomatically elevated serum levels of CA125 antigen, the diagnostic sensitivity, specificity, and accuracy of FDG- PET to detect recurrent ovarian cancers were 95.0%, 87.5%, and 92.9%, respectively. FDG-PET is a useful technique to detect recurrent ovarian cancers for patients suspected of recurrent ovarian cancers due to asymptomatically elevated serum levels of CA-125 antigen.en-USpositron emission tomography (PET)18T-fluoro-2-deoxyglucose (FDG)tumor marker (CA-125)ovarian cancer2ND-LOOK LAPAROTOMYCARCINOMA[SDGs]SDG3