Lin, B.-F.B.-F.LinJeng, S.-J.S.-J.JengBI-FONG LIN2018-09-102018-09-10199702715317http://www.scopus.com/inward/record.url?eid=2-s2.0-0030899386&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/334236https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030899386&doi=10.1016%2fS0271-5317%2897%2900068-7&partnerID=40&md5=98d83bc9443bb0bd4ffa2a56dc823504Two groups of NZB/W F1 mice were fed with diets containing 20% fresh and frying oils respectively. Serum levels of lipids, and anti-cardiolipin antibodies were followed regularly. The mice were sacrificed five months after feeding the experimental diets, the data showed: 1) body weight of mice fed frying oil was lower compared to that of fresh oil group; 2) relative tissue weight of mice fed frying oil were significantly higher compared to that of fresh oil group (p < 0.05); 3) lower serum triglyceride level and higher cholesterol level were noted in mice fed with frying oil compared to those of fresh oil group; 4) both hepatic triglyceride and phospholipid levels were significantly lower in mice fed with frying oil; 5) IgG anti- cardiolipin antibody was found to be higher in mice fed dietary frying oil compared to that of mice fed fresh oil; 6) microsomal cytochrome P-450 content was significantly higher in mice fed frying oil compared to that of the fresh oil group; 7) higher serum estrogen levels were noted in mice fed with frying oil compared to those of fresh oil group. The data demonstrated dietary oil did affect lipid and anti-cardiolipin antibody levels in autoimmune mice.Anti-cardiolipin antibody; Dietary frying oil; Estradiol; NZBxNZW F1 mice; Systemic lupus erythematosuscardiolipin antibody; cholesterol; cytochrome p450; estradiol; phospholipid; triacylglycerol; vegetable oil; animal model; animal tissue; antibody blood level; article; cholesterol blood level; controlled study; disease severity; fat intake; female; lipid liver level; lipid oxidation; mouse; nonhuman; priority journal; systemic lupus erythematosus; triacylglycerol blood leveljournal article10.1016/S0271-5317(97)00068-72-s2.0-0030899386WOS:A1997WW15600011