Chen S.-H.Chen Y.SHENG-HONG TSENG2020-03-122020-03-1220061016-3190https://www.scopus.com/inward/record.uri?eid=2-s2.0-33644653695&partnerID=40&md5=06e36df9283225374aaa880d378fb893https://scholars.lib.ntu.edu.tw/handle/123456789/476179Contact dermatitis from topical corticosteroids is quite common; however, anaphylactoid reactions to systemic corticosteroids are rare. A 50-year-old man suffered from acute cervical spinal cord injury with quadriplegia after a vehicle accident. A total of 500 mg methylprednisolone sodium succinate (MPSS) was given intravenously and the patient developed cardiovascular collapse soon after administration. After resuscitation, he became stable. Re-challenge with intravenous injection of 40 mg MPSS induced skin rash without changes of vital signs. We present the rare occurrence of anaphylactoid reaction to MPSS and reviewed the literature.Anaphylactoid reaction; Corticosteroid; Methylprednisolone[SDGs]SDG3betamethasone; clobetasone butyrate; corticosteroid; hydrocortisone; methylprednisolone sodium succinate; triamcinolone; adult; anaphylaxis; article; case report; contact dermatitis; drug megadose; human; male; provocation test; quadriplegia; rash; resuscitation; shock; spinal cord injury; traffic accidentjournal article2-s2.0-33644653695