2012-08-012024-05-17https://scholars.lib.ntu.edu.tw/handle/123456789/689227摘要：中文字的義音形交互作用歷程的神經機制此研究計畫的主旨是探討語意處理的神經機制，並研究閱讀中文時如何由語音和字形獲得意義的歷程。藉由認知處理所活化的個別腦區，和不同腦區之間的有效性聯結，將能對於中文字的詞彙辨識系統的功能組織有更多的瞭解。參與者將進行語意判斷作業，決定兩個出現的中文字是否在意義上有關聯。實驗的刺激材料分為三組：高語意相關字對，低語意相關字對，及無關語意相關字對。此三年期的研究計畫將採用行為測量和功能性磁振造影，評估處理中文字義音形的認知歷程和對應的神經活動。第一年的計畫，將採用跨感官的音義轉換作業，用以評估音義詞彙表徵的對應轉換之交互作用。研究將觀察處理中文字的語音調節和認知控制的歷程。第二年的計畫，將採用字形相似性字對的形義轉換作業，用以評估形義詞彙表徵的對應轉換之交互作用。研究將觀察處理中文字的語意抑制和語意整合的歷程。第三年的計畫，將採用有效性聯結(動態因果推論模式)，用以評估義音形交互作用歷程在腦區間的方向性影響。研究將觀察前額葉和其他腦區之間，由上而下和由下而上的相互影響。此研究計畫的預期成果，將對於中文字的義音形交互作用歷程的神經機制有更進一步的瞭解。<br> Abstract: Neural correlates of interaction between meaning, sound, and visual form for processing Chinese charactersThis project is to explore how semantic processing is affected by sound and visual form processing during reading Chinese characters. Cognitive processes associated with distinct brain regions and connectivity between brain regions will be used to understand the functional architecture of word recognition systems for reading Chinese characters. Participants will be asked to judge if two Chinese characters are related in meaning. Experimental materials will be classified as three types of character pairs: closely related pairs, distantly related pairs, and unrelated pairs. This is a three-year project using functional magnetic resonance imaging (fMRI) and effective connectivity to investigate the semantic network. For the first-year, a cross-modal semantic association task will be used to examine the interaction of meaning and sound. This study will investigate phonological mediation versus cognitive control during processing Chinese characters. For the second-year, the visually similar of character pairs will be manipulated to examine the interaction of meaning and visual form. This study will focus on semantic suppression versus semantic enhancement during processing Chinese characters. For the third-year, effective connectivity (dynamic causal modeling) will be used to investigate how cognitive function emerges from the directional flow of information among brain regions during language processing. The aim of this study is to understand the top-down and bottom-up communication among frontal and other brain regions. The expected findings will advance our knowledge of neural correlates of interaction among meaning, sound, and visual form for processing Chinese characters.語音字形語意關聯功能性磁振造影有效性聯結phonologyorthographysemantic associationfMRIeffective connectivity