內科LAI, YUNG-CHANGYUNG-CHANGLAIHSIEN-LI KAOYEN-HUNG LINMAO-SHIN LINYI-LWUN HOCHIA-LUN CHAO2009-12-182018-07-112009-12-182018-07-112008http://ntur.lib.ntu.edu.tw//handle/246246/174564https://www.scopus.com/record/display.uri?eid=2-s2.0-54449086836&origin=inward&txGid=9e9d5d502f3663dc9cf0edb5337b2d0dThis study evaluated the efficacy and safety of use of the Angio-Seal vascular closure device deployment for early ambulation (2 h) after elective percutaneous coronary intervention in 143 consecutive patients receiving either intravenous low-dose enoxaparin (0.5 mg/kg) or unfractionated heparin (UFH). The initial success rate of Angio-Seal(trade mark) deployment was 98.6%, with no significant difference between the UFH group (98.9%) and the enoxaparin group (98.0%). In-hospital and clinic outcomes were evaluated in the 141 patients with successful Angio- Seal deployment. During hospitalization, there were no deaths, myocardial infarction, urgent target vessel revascularization or bleeding events in either group; three patients in the UFH group and none in the enoxaparin group had minor vascular complications (differences not significant). In clinic follow-up, two patients in the UFH group and none in the enoxaparin group had major vascular complications (differences not significant). Routine use of the Angio-Seal(trade mark) for early ambulation in patients receiving intravenous low-dose enoxaparin compared with UFH provides promising efficacy and safety for daily practice.en-USENOXAPARINUNFRACTIONATED HEPARINANGIO-SEAL (TM)VASCULAR CLOSURE DEVICEPERCUTANEOUS CORONARY INTERVENTIONjournal article10.1177/14732300080360052718831904