Effect of ropivacaine on endothelium-dependent phenylephrine-induced contraction in guinea pig aorta

PEI-LIN LINHUI-HSUN HUANGSHOU-ZEN FANTsai, M CM CTsaiLin, C HC HLinCHI-HSIANG HUANG2023-12-122023-12-122007-110001-5172https://scholars.lib.ntu.edu.tw/handle/123456789/637759Previous studies have shown that ropivacaine has biphasic vascular effects, causing vasoconstriction at low concentrations and vasorelaxation at high concentrations. This study was designed to examine the role of the endothelium during accidental intravascular absorption of ropivacaine, and to elucidate the mechanisms responsible.enEndothelium | Local anesthetic | Ropivacaine | Vasorelaxation[SDGs]SDG3Effect of ropivacaine on endothelium-dependent phenylephrine-induced contraction in guinea pig aortajournal article10.1111/j.1399-6576.2007.01443.x179446432-s2.0-35348956482https://api.elsevier.com/content/abstract/scopus_id/35348956482