Wei C.-M.HUEY-LING CHENPING-ING LEEChen C.-M.Ma C.-Y.WUH-LIANG HWU2020-03-102020-03-1020051034-4810https://www.scopus.com/inward/record.uri?eid=2-s2.0-22244451975&doi=10.1111%2fj.1440-1754.2005.00617.x&partnerID=40&md5=b3fdfaa88c5afe7c743fc2284dd2bb03https://scholars.lib.ntu.edu.tw/handle/123456789/475180Aspirin is commonly used as an anti-inflammatory therapy for Kawasaki syndrome. Early initiation with high dose aspirin (80 to > 100 mg/kg per day), followed by low-dose therapy at the afebrile stage, has been often used to reduce morbidity and mortality in coronary complications. We report a 10-month-old infant who was diagnosed with Kawasaki syndrome. Sudden onset of poor activity, poor appetite, lethargy, tachycardia, tachypnea, hepatomegaly, increased AST/ALT, coagulopathy and hyperammonemia developed 3 days after the high-dose aspirin therapy. His histopathological and ultrastructural findings from the liver biopsy were compatible with Reye's syndrome. He recovered completely, and there was no recurrence.English[SDGs]SDG3acetylsalicylic acid; glucose; mannitol; anamnesis; article; blood clotting disorder; case report; clinical feature; hepatomegaly; histopathology; human; hyperammonemia; infant; laboratory test; lethargy; liver biopsy; liver cell; male; mucocutaneous lymph node syndrome; physical examination; priority journal; Reye syndrome; tachycardia; tachypnea; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Infant; Male; Mucocutaneous Lymph Node Syndrome; Reye Syndrome; Taiwanjournal article10.1111/j.1440-1754.2005.00617.x159533352-s2.0-22244451975