2021-01-012024-05-17https://scholars.lib.ntu.edu.tw/handle/123456789/678722CO2 is a chemically inert molecule. The conversion of CO2 into complex structures often require nucleophilic, high-energy, or transition metal-based reagents. Moreover, harsh conditions, such as high temperature and pressure, are also involved. American chemical society estimates that many transition metals are faced with limited availability, rising threat, or serious threat in the next 100 years. Therefore, to develop the CO2 functionalization by the use of earth-abundant reagents, such as carbon or iron-based molecules, under mild reaction conditions appears to be a promising approach. In this proposal, we aim at investigating the existing CO2 coupling reactions and expanding the synthetic applicability to access to other substances. The CO2 coupling reactions include synthesis of α-amino acids, synthesis of acrylic acid, synthesis of oxalic acid, and synthesis of salicylic acid. Single electron transfer is the primary tactic in the syntheses. DFT calculations will be carried out to look into the reaction mechanism and assist in finding suitable reagents being active in the CO2 coupling reactions. It is envisaged that the acquired knowledge and techniques will be not only academically intriguing, but also industrially applicable.CO2 conversion, coupling reaction, earth-abundant reagent, DFT calculations, single electron transfer