KUO-CHIN HUANGKormas N.Steinbeck K.Loughnan G.Caterson I.D.2021-01-142021-01-1420041071-7323https://www.scopus.com/inward/record.uri?eid=2-s2.0-4644251970&doi=10.1038%2foby.2004.101&partnerID=40&md5=7dc05f4fa7369fa4dcbd7ab3e0687ad4https://scholars.lib.ntu.edu.tw/handle/123456789/540755Objectives: To compare the resting metabolic rate (RMR) between diabetic and nondiabetic obese subjects and to develop a predictive equation of RMR for these subjects. Research Methods and Procedures: Obese adults (1088; mean age = 44.9 ± 12.7 years) with BMI ? 35 kg/m2 (mean BMI = 46.4 ± 8.4 kg/m2) were recruited. One hundred forty-two subjects (61 men, 81 women) were diagnosed with type 2 diabetes (DM), giving the prevalence of DM in this clinic population as 13.7%. RMR was measured by indirect calorimetry, and several multivariate linear regression models were performed using age, gender, weight, height, BMI, fat mass, fat mass percentage, and fat-free mass as independent variables. Results: The severely obese patients with DM had consistently higher RMR after adjustment for all other variables. The best predictive equation for the severely obese was RMR = 71.767 - 2.337 x age + 257.293 x gender (women = 0 and men = 1) + 9.996 x weight (in kilograms) + 4.132 x height (in centimeters) + 145.959 x DM (nondiabetic = 0 and diabetic = 1). The age, weight, and height-adjusted least square means of RMR between diabetic and nondiabetic groups were significantly different in both genders. Discussion: Severely obese patients with type 2 diabetes had higher RMR than those without diabetes. The RMR of severely obese subjects was best predicted by an equation using age, gender, weight, height, and DM as variables. Copyright ? 2004 NAASO.Diabetes; Prediction; Resting metabolic rate; Severely obese[SDGs]SDG3adult; aging; article; basal metabolic rate; body height; body mass; body weight; diabetes mellitus; female; glucose blood level; human; male; metabolism; middle aged; non insulin dependent diabetes mellitus; obesity; retrospective study; statistical model; Adult; Aging; Basal Metabolism; Blood Glucose; Body Height; Body Mass Index; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; Male; Middle Aged; Obesity; Retrospective Studiesjournal article10.1038/oby.2004.101151663052-s2.0-4644251970