Hsu S.-S.MING-HSIA HUWang Y.-H.Yip P.-K.Chiu J.-W.CHING-LIN HSIEH2020-06-292020-06-2920100039-2499https://www.scopus.com/inward/record.uri?eid=2-s2.0-77950223630&doi=10.1161%2fSTROKEAHA.109.574160&partnerID=40&md5=82ded868e179c60f1d2785cbcff7ea8bhttps://scholars.lib.ntu.edu.tw/handle/123456789/506466BACKGROUND AND PURPOSE-: The purpose of our study was to investigate the effects of different doses of neuromuscular electrical stimulation (NMES) on upper-extremity function in acute stroke patients with severe motor deficit. METHODS-: Sixty-six acute stroke patients were randomized to 3 groups: high NMES, low NMES, or control. The low-NMES group received 30 minutes of stimulation per day, and the high-NMES group received 60 minutes per day, for 4 weeks. The Fugl-Meyer Motor Assessment Scale, Action Research Arm Test, and Motor Activity Log were used to assess the patients at baseline, 4 weeks, and 12 weeks post baseline (follow-up). RESULTS-: Both NMES groups showed significant improvement on Fugl-Meyer Motor Assessment and Action Research Arm Test scales compared with the control group at week 4 and follow-up. The high-NMES group showed treatment effects similar to those of the low-NMES group. CONCLUSIONS-: Higher and lower doses of NMES led to similar improvements in motor function. A minimum of 10 hours of NMES in combination with regular rehabilitation may improve recovery of arm function in stroke patients during the acute stage. ? 2010 American Heart Association, Inc.[SDGs]SDG3adult; aged; arm movement; article; clinical trial; controlled clinical trial; controlled study; disease severity; female; follow up; human; major clinical study; male; motor activity; motor dysfunction; motor performance; neuromuscular electrical stimulation; outcome assessment; priority journal; randomized controlled trial; rating scale; single blind procedure; stroke; treatment duration; Adult; Aged; Aged, 80 and over; Electric Stimulation Therapy; Humans; Male; Middle Aged; Motor Activity; Stroke; Treatment Outcome; Upper Extremityjournal article10.1161/STROKEAHA.109.574160202033212-s2.0-77950223630