Chiang, Chi-FengChi-FengChiangHsu, Yuan-HungYuan-HungHsuHsieh, Wen-YuanWen-YuanHsiehLiao, Tzu-HsinTzu-HsinLiaoChen, Chih-LungChih-LungChenChen, Yung-ChuYung-ChuChenPO-CHIN LIANGWang, Shian-JyShian-JyWang2023-09-062023-09-062023-02-1110531807https://scholars.lib.ntu.edu.tw/handle/123456789/635119MRI is crucial in diagnosing hepatocellular carcinoma (HCC). Superparamagnetic iron oxide particles (SPIO) are liver-specific contrast agents which enhance lesions in T2 -weighted images. Iron oxide nano-particle m-PEG-silane (IOP) Injection, a newly developed SPIO, showed promising imaging effects and good safety profile in preclinical studies and in phase I clinical trial.enhepatocellular carcinoma; liver specific contrast agent; magnetic resonance imaging; superparamagnetic iron oxide particles[SDGs]SDG3IOP Injection, A Novel Superparamagnetic Iron Oxide Particle MRI Contrast Agent for the Detection of Hepatocellular Carcinoma: A Phase II Clinical Trialjournal article10.1002/jmri.28645367730052-s2.0-85148516703https://api.elsevier.com/content/abstract/scopus_id/85148516703