MING-CHU CHANGJAU-MIN WONGYU-TING CHANG2021-02-042021-02-0420141007-9327https://www.scopus.com/inward/record.uri?eid=2-s2.0-84895875508&doi=10.3748%2fwjg.v20.i9.2358&partnerID=40&md5=717c701db86d94389de8e9b3ee97ec0dhttps://scholars.lib.ntu.edu.tw/handle/123456789/548368Pancreatic cancer is a serious growing health issue in developed countries. For patients diagnosed with pancreatic cancer, the five year survival rate is below 5%. One major important reason leads to the poor survival rate is lack of early detection of pancreatic cancer. Over 80% of the patients are diagnosed in advanced disease stages. Screening for pancreatic cancer is a desirable option for high risk individuals to allow early detection and treatment of curable pancreatic neoplasms at a pre-invasive stage. This article highlights the need, endpoint, population, method, diagnostic yield, and the problems of current screening programs. ? 2014 Baishideng Publishing Group Co., Limited. All rights reserved.[SDGs]SDG3CA 19-9 antigen; article; cancer grading; cancer screening; computer assisted tomography; diabetic patient; endoscopic echography; familial atypical multiple mole melanoma syndrome; familial cancer; familial pancreas cancer; gene mutation; hereditary breast and ovarian cancer syndrome; hereditary nonpolyposis colorectal cancer; high risk population; human; magnetic resonance cholangiopancreatography; nuclear magnetic resonance imaging; obesity; pancreas cancer; pancreatitis; Peutz Jeghers syndrome; smoking; tumor suppressor gene; diagnostic imaging; early diagnosis; Pancreatic Neoplasms; patient selection; predictive value; procedures; prognosis; risk assessment; risk factor; time; Diagnostic Imaging; Early Detection of Cancer; Humans; Pancreatic Neoplasms; Patient Selection; Predictive Value of Tests; Prognosis; Risk Assessment; Risk Factors; Time FactorsScreening and early detection of pancreatic cancer in high risk populationjournal article10.3748/wjg.v20.i9.2358246050332-s2.0-84895875508