邱文英2006-07-252018-06-282006-07-252018-06-282002-08-25http://ntur.lib.ntu.edu.tw//handle/246246/9274本研究主要是以分散相聚合法獲得幾丁聚醣與聚醋酸乙烯酯接枝共聚物，其分散相水溶液再經醇化獲得幾丁聚醣與聚乙烯醇接枝共聚物。將水溶液直接烘乾成膜，結果得到的是顆粒膜，且在顆粒表面富含幾丁聚醣。將此材料應用於銅離子吸附上，其吸附過程是擴散模式控制，而其擴散係數會隨幾丁聚醣含量增加而增加。以戊二醛進行交聯過後的材料，其機械性質有明顯的改善，但吸水度與銅離子吸附總量均下降。幾丁聚醣與聚乙烯醇接枝共聚物在細胞培養上，發現幾丁聚醣的加入明顯改善了細胞在材料上的貼附，使得細胞活性增加。應用在血液適合性方面，發現有一最適合的組成，其材料吸附血小板的量為最低。在生物分解性測試上，幾丁聚醣與聚乙烯醇接枝共聚物在48 小時後會完全分解。Chitosan/vinyl acetate graft copolymers were prepared by using a redox initiator. With further alcoholysis, chitosan/vinyl alcohol copolymers were obtained. During the adsorption of copper ion, two-stage behavior was observed. In the first stage, the adsorption was governed by both the diffusion and reaction; whereas only diffusion controlled the second stage. The diffusion coefficient increased with the amount of chitosan content. If cross-linked with the glutaraldehyde, both of the degree of swelling and adsorption quantity of copper decreased with the extent of cross-linking. In the cell culture of osteoblast, the addition of chitosan improves the adhesion of cells. An optimum composition was found for the chitosan/vinyl alcohol copolymers in the blood compatibility. After 48 hours, the copolymers were degraded completely.application/pdf61257 bytesapplication/pdfzh-TW國立臺灣大學化學工程學系暨研究所幾丁聚醣接枝共聚合體聚醋酸乙烯酯聚乙烯醇chitosangraft copolymerpoly(vinyl acetate)poly(vinyl alcohol)reporthttp://ntur.lib.ntu.edu.tw/bitstream/246246/9274/1/892216E002035.pdf