CHIEN-HUA HUANGKUO-LIONG CHIENWEN-JONE CHENSung F.-C.Hsu H.-C.TA-CHEN SULee Y.-T.2020-02-272020-02-2720071388-9842https://scholars.lib.ntu.edu.tw/handle/123456789/466178Background: There is little community-based information on heart failure (HF) prognosis in ethnic Chinese populations, in whom there is a low prevalence of coronary heart disease. Aims: To study the impact of HF and left ventricular function on long-term all-cause mortality. Methods and results: This community-based prospective cohort study included 2660 subjects (1215 men, 1445 women, mean age 54.4 ± 11.9?years) over a 10?year follow-up period. The prevalence of HF was 5.5%. Hypertension was the most common factor related to HF. The five and ten year all-cause mortality was higher in the HF/preserved LVEF group (14.1% and 24.4%) and the HF/impaired LVEF group (29.2% and 48.2%) than in the HF-free group (6.0% and 14.6%, p < 0.0001 for both). In multivariable Cox analyses, controlling for sex, LV mass, atrial fibrillation, hypertension, coronary heart disease, HF/preserved LVEF and HF/impaired LVEF were important predictors of all-cause mortality (p = 0.007). Conclusions: Hypertension is a major heart failure related disease. HF and LV systolic dysfunction are associated with a significant increase in all-cause mortality in an ethnic Chinese population. ? 2007 European Society of Cardiology.[SDGs]SDG3adult; aged; article; community care; comorbidity; controlled study; diabetes mellitus; disease association; echocardiography; ethnicity; female; heart atrium fibrillation; heart failure; heart left ventricle function; human; hypertension; ischemic heart disease; major clinical study; male; mortality; prevalence; priority journal; prognosis; survival; systolic dysfunction; Taiwan; Adult; Aged; Cause of Death; Cohort Studies; Female; Follow-Up Studies; Heart Failure, Congestive; Humans; Hypertension; Male; Middle Aged; Risk Factors; Survival Analysis; Survivors; Taiwan; Ventricular Dysfunction, Leftjournal article10.1016/j.ejheart.2007.02.008173981552-s2.0-34247866374