流行病學研究所;Graduate Institute of EpidemiologyHUNG, CHIN-CHUANCHIN-CHUANHUNGTAI, JOHN JENJOHN JENTAILIOU, HORNG-HUEIHORNG-HUEILIOU2008-09-252018-06-292008-09-252018-06-292006http://ntur.lib.ntu.edu.tw//handle/246246/81982Objectives A broad range of phenytoin doses is used in clinical practice, with the final 'maintenance' dose normally determined by trial and error. A common functional polymorphism in the SCN1A gene (one of the genes encoding the drug target) has been preen-USassociation geneticsdrug responseepilepsymaintenance dosepharmacodynamicspharmacogeneticsjournal article