YA-PING HUANGFann C.-Y.Chiu Y.-H.Yen M.-F.Chen L.-S.Chen, Tony Hsiu HsiTony Hsiu HsiChenSHIN-LIANG PAN2020-04-072020-04-0720132151-464Xhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84879733752&doi=10.1002%2facr.21938&partnerID=40&md5=bc63cc3f3ba376b86ec708881dec6956https://scholars.lib.ntu.edu.tw/handle/123456789/482881Objective Although it has been suggested that diabetes mellitus (DM) is a risk factor for developing adhesive capsulitis of the shoulder (ACS), data on the temporal association between these 2 conditions are sparse. The purpose of this population-based age- and sex-matched cohort study was to investigate the risk of developing ACS in patients with newly diagnosed DM. Methods A total of 78,827 subjects with at least 2 ambulatory care visits with a principal diagnosis of DM in 2001 were recruited for the DM group. The non-DM group comprised 236,481 age- and sex-matched randomly sampled subjects without DM. The 3-year cumulative risk of ACS was calculated using the Kaplan-Meier method. A Cox proportional hazards regression model was used to estimate the crude and adjusted hazard ratio (HR) of developing ACS. Results During a 3-year followup period, 946 subjects (1.20%) in the DM group and 2,254 subjects (0.95%) in the non-DM group developed ACS. The crude HR of developing ACS for the DM group compared to the non-DM group was 1.333 (95% confidence interval [95% CI] 1.236-1.439, P < 0.0001), whereas the adjusted HR was 1.321 (95% CI 1.224-1.425, P < 0.0001) after adjustment for age, sex, and dyslipidemia. Conclusion This longitudinal population-based followup study showed that there is a significantly increased risk of developing ACS after developing DM. Copyright ? 2013 by the American College of Rheumatology.[SDGs]SDG3adhesive capsulitis of the shoulder; adult; aged; ambulatory care; article; diabetes mellitus; disease association; dyslipidemia; female; follow up; hazard ratio; human; humeroscapular periarthritis; major clinical study; male; population based case control study; risk; Adult; Aged; Bursitis; Case-Control Studies; Chi-Square Distribution; Diabetes Complications; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Longitudinal Studies; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Shoulder Joint; Taiwan; Time Factorsjournal article10.1002/acr.21938232813422-s2.0-84879733752