Dept. of Electr. Eng., National Taiwan Univ.Lee, I.-Y.I.-Y.LeeLin, W.-C.W.-C.LinHo, J.-M.J.-M.HoWang, G.-L.G.-L.WangMING-SYAN CHEN2018-09-102018-09-102005http://www.scopus.com/inward/record.url?eid=2-s2.0-33846980462&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/316178Laboratories worldwide are working on EST cDNA library and microarray projects, each project involving hundreds to hundreds of thousands of clones. To support the needs of individual laboratories, an efficient EST sequence management system is needed. Here we describe BIO101, a centralized approach to laboratory EST sequence management and functional annotation. The system includes a) laboratory-based authorization, project-focused and custom database management features; b) a pipeline with integrated tools for producing and clustering high-quality ESTs and for identifying homologues; c) a pipeline scheduling mechanism that emphasizes fairness; and d) collaborative manual and automatic functional annotation features. BIO101 is accessible to registered members at http://bio101.iis.sinica.edu.tw/. © 2005 IEEE.application/pdf771257 bytesapplication/pdfAnnotation; Expressed sequence tags; Sequence management[SDGs]SDG9Database systems; DNA; Quality assurance; Scheduling; Annotation; Expressed sequence tags; Laboratory based authorization; Sequence management; Management information systemsconference paper10.1109/ISSPIT.2005.15770672-s2.0-33846980462