2017-01-012024-05-17https://scholars.lib.ntu.edu.tw/handle/123456789/679332摘要：本計畫以高溫超導量子干涉元件(High-Tc Superconducting Quantum Interference Device, HT SQUID)陣列製作腦磁圖（Magnetoencephalography，MEG）量測系統，應用於動物腦磁圖研究，製程將挑戰HT SQUID特性之極限，能與傳統低溫超導SQUID高靈敏、低雜訊特性相媲美，以降低對昂貴液態氦之依賴。且突破SQUID陣列串音效應(crosstalk effect)之極限，提高空間解析度至5 mm以下，相較於目前低溫超導MEG之~15 mm空間解析度。此外，將高溫超導SQUID MEG應用於動物腦神經病變機制研究，彌補現今以腦電圖研究之不足。<br> Abstract: In this project, high-Tc Superconducting Quantum Interference Device (HT SQUID) arrays will be fabricated to establish a magnetoencephalography (MEG) system for the application on studies of animal MEG. The fabrication will challenge the limit of the HT SQUID features that can be comparable to those of traditional low-temperature superconducting SQUIDs with high sensitivity and low noise characteristics to reduce dependence on expensive liquid helium. It will also break through the limits of the crosstalk effect on the SQUID array, and increase the spatial resolution to less than 5 mm, which is comparable to the spatial resolution of ~ 15 mm for the current low-Tc superconducting MEG system. In addition, the HT SQUID MEG system will be applied on the studies of animal neuropathy mechanisms to make up the current researches with electroencephalography (EEG) systems.高溫超導量子干涉元件磁性感測元件陣列串音效應HTS SQUIDmagnetic detectorarraycrosstalk effect