SHIH-JUNG CHENGHUI-HSIN KOJANG-JAER LEESANG-HENG KOK2021-07-062021-07-0620181043-3074https://www.scopus.com/inward/record.uri?eid=2-s2.0-85034236805&doi=10.1002%2fhed.24994&partnerID=40&md5=9be2da6e855ad4f314d1e90453fd9fe6https://scholars.lib.ntu.edu.tw/handle/123456789/569668Background: The purpose of this study was to determine whether the pull-through resection is better than the mandibular lip-split for advanced tongue/floor of mouth (FOM) cancers, which remains inconclusive. Methods: A retrospective cohort study was performed on 91 patients with T4a tongue/FOM cancers from 2009 to 2014. Cases with mandibular resection were excluded. The pull-through resection was used when the mouth opening was ?15 mm; otherwise the mandibular lip-split was used. Results: Fifty-eight patients received pull-through resections and 33 underwent mandibular-lip splits and the mean follow-up periods were 42 and 45 months, respectively. Surgical margin, locoregional recurrence, and 5-year survival were similar between the 2 groups. The pull-through approach had a significantly shorter operation time, lower rates of flap infection, osteoradionecrosis, metal plate exposure, loss of tooth vitality, and better aesthetics. Conclusion: Our data suggest that the pull-through resection does not compromise disease control for advanced tongue/FOM cancers and is superior to the mandibular lip-split in terms of operation time, postoperative complications, and aesthetics. ? 2017 Wiley Periodicals, Inc.[SDGs]SDG3adult; aged; Article; bone necrosis; cancer recurrence; cohort analysis; controlled study; esthetics; female; follow up; human; infection; intermethod comparison; major clinical study; male; mandible resection; mandibular lip split surgery; mouth cancer; mouth floor; operation duration; outcome assessment; postoperative complication; priority journal; pull through operation; retrospective study; surgical margin; surgical technique; survival analysis; tongue cancer; cancer staging; cancer survivor; comparative study; disease free survival; evaluation study; glossectomy; head and neck tumor; mandible osteotomy; middle aged; mortality; mouth floor; nonparametric test; pathology; procedures; risk assessment; squamous cell carcinoma; Taiwan; time factor; tongue tumor; tumor invasion; tumor recurrence; Adult; Aged; Cancer Survivors; Carcinoma, Squamous Cell; Cohort Studies; Disease-Free Survival; Female; Follow-Up Studies; Glossectomy; Head and Neck Neoplasms; Humans; Male; Mandibular Osteotomy; Middle Aged; Mouth Floor; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Risk Assessment; Statistics, Nonparametric; Survival Analysis; Taiwan; Time Factors; Tongue Neoplasmsjournal article10.1002/hed.24994291405812-s2.0-85034236805