Yang F.-C.Chen H.-M.Huang C.-M.Hsieh P.-L.SHOEI-SHEN WANGChen C.-M.2021-05-112021-05-1120201661-7827https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089467925&doi=10.3390%2fijerph17165798&partnerID=40&md5=4306f2be0e565bf901dfc05ea2101e3chttps://scholars.lib.ntu.edu.tw/handle/123456789/560660With recent advances in surgery and immunosuppressive drugs, organ transplantation has become a major treatment for irreversible organ failure. However, organ transplant recipients returning home after operation may face ongoing physiological, psychological, and social difficulties. To increase recipients’ quality of life, postoperative care at home is critical. Thus, the aim of this systematic literature review was to explore recipients’ difficulties and needs during postoperative care at home. Our search conformed to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and returned 23 relevant articles published from 1997–2020 in PubMed, MEDLINE, EBSCO, Cochrane, ProQuest, and CEPS, which were assessed using the Modified Jadad Scale or the 32 Consolidated Criteria for Reporting Qualitative Research (COREQ) appraisal indices and then synthesized through narration. The most common difficulties faced were psychological difficulties, followed by physiological, social, and other difficulties; the most common needs were psychological needs, followed by education and information training, social, and other needs. These results demonstrated that healthcare professionals can do more to provide patients with comprehensive care and promote successful self-management and quality of life at home. They also confirmed that collaboration between transplant teams, caregivers, and patients is necessary to optimize postoperative outcomes. We suggest that customized care may promote postoperative patients’ self-management and quality of life at home. ? MDPI AG. All rights reserved.Difficulties; Needs; Nursing; Postoperative care; Systematic review; Transplantation[SDGs]SDG3drug; health care; health worker; psychology; public health; quality of life; anxiety; Article; caregiver; depression; fatigue; graft failure; graft recipient; health care need; health care personnel; home care; human; organ transplantation; postoperative care; postoperative pain; public-private partnership; quality of life; self care; sleep disorder; social stress; spiritual care; systematic review; adolescent; adult; aged; child; cohort analysis; cross-sectional study; female; male; middle aged; quality of life; retrospective study; very elderly; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Child; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Postoperative Care; Quality of Life; Retrospective Studies; Transplant Recipients; Young Adultjournal article10.3390/ijerph17165798327965292-s2.0-85089467925