Chen S.-C.HSI-CHUNG CHENShih-Cheng LiaoTseng M.C.M.MING-BEEN LEE2020-06-262020-06-2620120163-8343https://www.scopus.com/inward/record.uri?eid=2-s2.0-84857371407&doi=10.1016%2fj.genhosppsych.2011.09.012&partnerID=40&md5=3e73d0a2dff5bd721a1d12359b98ca15https://scholars.lib.ntu.edu.tw/handle/123456789/504911Background: There have been numerous case reports of zolpidem abuse and dependence in the recent decade, giving rise to a focus on adverse withdrawal events such as seizure. No standard detoxification regimen has been proposed to date, despite the similarity of effects of zolpidem and benzodiazepines at high doses. Case Descriptions: We describe the results, in a 53-year-old female patient, of undergoing three different zolpidem detoxification programs. Conclusions: Because of her experiences, we recommend using the cross-titration strategy with an adequate equivalent dose of diazepam. ? 2012 Elsevier Inc..[SDGs]SDG3benzodiazepine; clonazepam; diazepam; flunitrazepam; paroxetine; quetiapine; sertraline; zolpidem; adult; anxiety; article; bedtime dosage; case report; drug absorption; drug abuse; drug dependence; drug detoxification; drug dose escalation; drug dose increase; drug dose reduction; drug dose titration; drug effect; drug half life; drug megadose; drug tolerability; drug withdrawal; female; heart palpitation; human; insomnia; irritability; loading drug dose; psychological aspect; seizure; side effect; tremor; withdrawal syndromejournal article10.1016/j.genhosppsych.2011.09.0122-s2.0-84857371407