The Combination of Daptomycin with Fosfomycin is More Effective than Daptomycin Alone in Reducing Mortality of Vancomycin-Resistant Enterococcal Bloodstream Infections: A Retrospective, Comparative Cohort Study

TAI-CHUNG TSENGYU-CHUNG CHUANGYang, Jia-LingJia-LingYangLin, Chi-YingChi-YingLinHuang, Sung-HsiSung-HsiHuangJANN-TAY WANGYEE-CHUN CHENSHAN-CHWEN CHANG2023-02-142023-02-142023-01-112193-8229https://scholars.lib.ntu.edu.tw/handle/123456789/627972High-dose daptomycin-based combinations are recommended for vancomycin-resistant Enterococcus (VRE) bloodstream infection (BSI). Preclinical data have shown a synergistic effect of daptomycin/fosfomycin combinations against VRE. However, clinical studies comparing daptomycin monotherapy with daptomycin/fosfomycin combinations are unavailable.enCombination; Daptomycin; Fosfomycin; Mortality; Vancomycin-resistant enterococci[SDGs]SDG3The Combination of Daptomycin with Fosfomycin is More Effective than Daptomycin Alone in Reducing Mortality of Vancomycin-Resistant Enterococcal Bloodstream Infections: A Retrospective, Comparative Cohort Studyjournal article10.1007/s40121-022-00754-1366299972-s2.0-85146057745WOS:000912322200002