Tsai, Yu-JenYu-JenTsaiChung, Wen-ChengWen-ChengChungWang, Lian-ChenLian-ChenWangYU-TEN JUHong, Chin-LinChin-LinHongTsai, Yu-YangYu-YangTsaiLi, Yi-HungYi-HungLiWu, Ying-LingYing-LingWu2018-09-102018-09-102011http://www.scopus.com/inward/record.url?eid=2-s2.0-80052098173&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/362211Infection rate, reaction to light, and hair follicle apoptosis are examined in the dogmite, Demodex canis Leydig (Prostigmata: Demodicidae), in dogs from the northern area of Taiwan. An analysis of relevant samples revealed 7.2% (73/1013) prevalence of D. canis infection. Infection during the investigation peaked each winter, with an average prevalence of 12.5% (32/255). The infection rates significantly varied in accordance with month, sex, age, and breed (p < 0.05). Most of the lesions were discovered on the backs of the infected animals, where the infection rate was 52.1% (38/73) (P < 0.05). The epidemiologic analysis of infection based on landscape area factor, found that employing a map-overlapping method showed a higher infection rate in the eastern distribution of Taiwan's northern area than other areas. Isolation tests for Microsporum canis Bodin (Onygenales: Arthrodermataceae) and Trichophyton mentagrophyte Robin (Blanchard) on the D. canis infected dogs revealed prevalence rates of 4.4% (2/45) and 2.2% (1/45), respectively. Observations demonstrated that D. canis slowly moved from a light area to a dark area. Skin samples were examined for cellular apoptosis by activated caspase3 immunohistochemical staining. Cells that surrounded the infected hair follicles were activated caspase3-positive, revealing cell apoptosis in infected follicles via the activation of caspase3.fungi; map overlay; Taiwan[SDGs]SDG3Animals; Apoptosis; Comorbidity; Dermatomycoses; Dog Diseases; Dogs; Eosinophils; Female; Hair Follicle; Host-Parasite Interactions; Leukocyte Count; Light; Male; Microsporum; Mite Infestations; Mites; Prevalence; Taiwan; Trichophytonanimal; animal disease; apoptosis; article; comorbidity; dermatomycosis; dog; dog disease; eosinophil; female; hair follicle; host parasite interaction; isolation and purification; leukocyte count; light; male; microbiology; Microsporum; mite; mite infestation; parasitology; pathology; physiology; prevalence; Taiwan; Trichophytonjournal article10.1673/031.011.7601