2024-05-182024-05-18https://scholars.lib.ntu.edu.tw/handle/123456789/719250My research interests are centered around the following areas:(1)Clinical and translational research in hematological malignancies, particularly lymphoid malignancies, with emphasis on diagnosis, therapeutic strategies, and clinical outcomes; (2)Advanced targeted therapies and immunotherapies, including the clinical application and evaluation of novel therapeutic drugs, antibody treatments, and combination treatments;(3)Molecular genetics and signaling pathways involved in blood cancers, specifically related to lymphoma subtypes;(4)Application of advanced molecular biology techniques, proteomics, phosphoproteomics, and next-generation sequencing for biomarker discovery, disease monitoring, and understanding signaling mechanisms underpinning disease progression and treatment response. Overall, my work integrates clinical trials, molecular biology, genetics, proteomics, and translational medicine approaches aimed at improved diagnostic precision, therapeutic effectiveness, and mechanistic insights into hematologic cancers.第一，如何利用每一個不同淋巴細胞專屬獨有的基因重組序列，協助確認困難診斷的淋巴癌病案，並進行治療後的微小殘餘量分析。其二是結合臺大醫院的人工智慧團隊發展淋巴癌治療成績即時監測與決策升級系統（Lymphoma Outcome of Treatment Monitoring & Decision-Making Upgrade System, LOTUS），協助辨認出針對每一位淋巴癌患者可能的最佳治療藍圖與策略。第三，目前針對臺灣最大的被套細胞淋巴癌與何杰金氏淋巴癌的世代研究，努力結合所有本地罕見淋巴癌病案，發掘尚未被完全了解的病態生理奧秘。