Lin Y.-C.CHANG-HAO YANGCHANG-PING LINCHUNG-MAY YANGMUH-SHY CHENChen M.-Y.WANG-HUEI SHENGCHIEN-CHING HUNGSHAN-CHWEN CHANG2020-12-302020-12-3020080927-3948https://www.scopus.com/inward/record.uri?eid=2-s2.0-45749087295&doi=10.1080%2f09273940802056307&partnerID=40&md5=c3edb41d26ecea13a1cee3503d8c923ehttps://scholars.lib.ntu.edu.tw/handle/123456789/536255Purpose: To determine the characteristics of cytomegalovirus (CMV) retinitis and immune recovery uveitis (IRU) in the era of highly active antiretroviral therapy (HAART). Methods: We reviewed data from 47 of 79 consecutive patients with acquired immunodeficiency syndrome (AIDS) and CMV retinitis. Results: The incidence of CMV retinitis in AIDS patients has markedly decreased over the recent 10 years. The characteristics of CMV retinitis have changed. Development of IRU occurred in 24.4%. Conclusions: Symptomatic IRU develops in a significant number of patients with inactive CMV retinitis following successful HAART. Eyes with IRU respond favorably to antiinflammatory therapy without reactivation of retinitis. Copyright ? Informa Healthcare USA, Inc.[SDGs]SDG3antiretrovirus agent; ganciclovir; triamcinolone; acquired immune deficiency syndrome; adult; article; controlled study; Cytomegalovirus; female; highly active antiretroviral therapy; human; immune reconstitution inflammatory syndrome; major clinical study; male; ophthalmoscopy; retina macula edema; retinitis; uveitis; virus reactivation; visual acuity; Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Cytomegalovirus Retinitis; Female; Humans; Immune System; Incidence; Male; Middle Aged; Recovery of Function; Retrospective Studies; Taiwan; Uveitisjournal article10.1080/0927394080205630718569793