2017-04-012024-05-13https://scholars.lib.ntu.edu.tw/handle/123456789/643036摘要：上位計畫配合「黃金十年、國家願景」政策，結合國內資通訊電子產業優勢，產學研醫合作，開發市場導向之高階影像醫療器材技術，以一旗艦產品原型機開發，期達到全面關鍵技術提升，填補當前我國主導產業轉型發展的缺口，帶動傳統產業技術升級及創新加值。醫用3D放射造影儀系統成像性能受系統軟硬體設計製造，包含組件選用等影響，會受到不同來源的雜訊干擾。造影系統輻射劑量高則訊號強，雜訊影響相對較小。但因上位計畫預建置低輻射劑量造影系統，訊號小雜訊影響相對大，進而影響影像品質。本計畫將建立一適用於3D放射造影儀系統之影像品質評估標準，首先將建立定量指標，包含量測模量傳遞函數(Modulation transfer function, MTF)及雜訊功率頻譜(Noise power spectrum, NPS)之方法，評估原型機產生之影像及找尋最佳化造影參數。此外，此研究將透過影像醫學部臨床醫師經驗及專長，透過與核研所合作討論，建立影像品質定性指標及允收標準。結合此定量及定性指標，期能兼顧影像品質並將劑量合理抑低，達到低劑量及高訊雜比3D放射造影之目的。最後將建立影像品質控制程序，做為未來臨床使用之標準。<br> Abstract: Three-dimensional medical radiological imaging system suffers from different noises from different sources according to the design and manufacturing of software and hardware, including component selection and other factors. If the radiation dose of angiography system is high, the signal intensity will be high and the impact of noise will be relatively small. However, the superior project aims to establish an angiography system using low radiation dose. The signal intensity will be low and the impact of noise will relatively be large, thereby affecting image quality. This project aims to establish a suitable standard 3D image quality assessment system of radiological imaging instrument. Firstly, we will establish quantitative indicators, including the modulation transfer function (MTF) and noise power spectrum (NPS). These methods will be performed to assess the image quality of prototype and find the best parameters of imaging acquisition. In addition, in this study, we will collect the suggestions from clinicians who have experience and expertise of medical imaging and discuss with the cooperators of Institute of Nuclear Energy research. We aim to establish the qualitative indicators of image quality acceptance criteria. Combining these quantitative and qualitative indicators, we aim to find a balance between image quality and radiation dose to achieve the goal of 3D radiological imaging, low-dose and high signal to noise ratio. Finally, we will provide the suggestions of the image quality control procedures of the 3D radiological imaging system, as the future standard for clinical use.3D放射造影儀系統核能Three-dimensional medical radiological imaging systemNuclear