Critical commentary on "The potential of a site-specific delivery of thiamine hydrochloride as a novel insect repellent exerting long-term protection on human skin: In-vitro, ex-vivo study and clinical assessment"

MATAN SHELOMI2023-03-312023-03-312022-080022-3549https://scholars.lib.ntu.edu.tw/handle/123456789/629950This letter comments on a recent article by Halawani et al. (10.1016/j.xphs.2021.07.017), which claimed a complex hydrogel formulation of thiamine nanospheres is a topical insect repellent. The authors did not thoroughly review the extensive prior literature on the subject that found no evidence of repellency for thiamine, and the experiment described lacked negative controls. Its results are not conclusive.enMosquito repellent; Nanospheres; Pullulan acetate; Skin protection; Thiamine hydrochloride[SDGs]SDG2[SDGs]SDG3Critical commentary on "The potential of a site-specific delivery of thiamine hydrochloride as a novel insect repellent exerting long-term protection on human skin: In-vitro, ex-vivo study and clinical assessment"journal article10.1016/j.xphs.2022.03.012358436542-s2.0-85133452043WOS:000829687700001https://api.elsevier.com/content/abstract/scopus_id/85133452043