Sriram BBaby J.NHsu Y.-FWang S.-FBenadict Joseph XGeorge MVeerakumar PKING-CHUEN LIN2022-04-252022-04-25202126376113https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116239737&doi=10.1021%2facsaelm.1c00506&partnerID=40&md5=1df1f7ca0d858a738147b22ce57eedc9https://scholars.lib.ntu.edu.tw/handle/123456789/606905In this work, hierarchically superior spinel crystalline manganese cobaltite (MnCo2O4) microflowers were hydrothermally synthesized to anchor on phosphorus-doped graphic carbon nitride nanosheet (MnCo2O4/P-CN) nanocomposites for the robust detection of the antibiotic sulfadiazine (SF). The structure and surface characteristics of the obtained composite were measured by the spectroscopic method, which collectively suggests the superior physical and chemical properties of the composite. The anodic oxidation of SF was considered at a glassy carbon electrode modified by MnCo2O4/P-CN (MnCo2O4/P-CN/GCE) using cyclic voltammetry (CV) and amperometry (i-t) techniques. A synergistic relationship between the high-quality flower-like MnCo2O4and P-CN materials provides high electrical conductivity, larger surface area, and increased surface-active sites. The results indicate that MnCo2O4/P-CN/GCE shows excellent electrocatalytic activity toward the anodic oxidation of SF in pharmaceutical contaminants present in the environment at buffered pH 7.0. The proposed sensor viai-tand differential pulse voltammetry (DPV) results exhibits a wide linear range (LR: 0.008-207.57 and 0.01-95.40 μM), lower detection limit (LOD: 1.2 and 3 nM), and good sensitivity (9.28 and 49.28 μM μA-1cm-2), respectively, as well as an excellent operational and cycle stability toward the electrochemical determination of SF. The unique structural features of a spinel crystalline MnCo2O4microflower with symmetrical petals and six trunks can progressively enhance the electrochemical performance of the SF sensor. The state-of-the-art analysis of real samples confirms the possible utilization of Mn-Co-based sensors toward the monitoring of antibiotic residues, thus helping in assessing the behavior of pharmaceutical contaminants in the environment. ? 2021 American Chemical Society3D spinelelectrochemical approachMnCo2O4P-doped carbon nitridereal-time analysisAnodic oxidationAntibioticsCarbon nitrideChemical detectionElectrocatalystsGlass membrane electrodesManganese compoundsSpectroscopic analysis3d spinelAntibiotic drugsElectrochemical approachElectrochemicalsHydrothermally synthesizedMicroflowersPharmaceutical contaminantsReal time analysisVoltammetric determinationCyclic voltammetryjournal article10.1021/acsaelm.1c005062-s2.0-85116239737