Stimulation phosphatidylinositol 3-kinase/protein kinase B signaling by Porphyromonas gingivalis lipopolysacch aride mediates interleukin-6 and interleukin-8 mRNA/protein expression in pulpal inflammation

YI-LING TSAICHEN-YING WANGChuang, Fu-HsiungFu-HsiungChuangPan, Yu-HwaYu-HwaPanLin, Yan-RuYan-RuLinDhingra, KunaalKunaalDhingraLiao, Pai-ShienPai-ShienLiaoHuang, Fong-ShungFong-ShungHuangChang, Mei-ChiMei-ChiChangJIIANG-HUEI JENG2023-05-042023-05-042023-010929-6646https://scholars.lib.ntu.edu.tw/handle/123456789/630816The signaling mechanisms for Porphyromonas gingivalis lipopolysaccharide (PgLPS)-induced inflammation in human dental pulp cells are not fully clarified. This in vitro study aimed to evaluate the involvement of phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway in PgLPS-induced pulpal inflammation.enHuman dental pulp cells; Inflammation; Interleukin; Porphyromonas gingivalis; Protein kinase B[SDGs]SDG3Stimulation phosphatidylinositol 3-kinase/protein kinase B signaling by Porphyromonas gingivalis lipopolysacch aride mediates interleukin-6 and interleukin-8 mRNA/protein expression in pulpal inflammationjournal article10.1016/j.jfma.2022.08.005360314862-s2.0-85139214904https://api.elsevier.com/content/abstract/scopus_id/85139214904