Zhao, LikeLikeZhaoCHIN-HSIU LIUYu, DavidDavidYu2023-05-252023-05-252011-060315-162Xhttps://scholars.lib.ntu.edu.tw/handle/123456789/631382Ankylosing spondylitis (AS) is a highly heritable disease with HLA-B27 being the strongest susceptible gene. In order to survey the environmental triggers for arthritis development, we used a high-throughput technique to screen the effects of 12,264 chemicals on the HLA-B27 gene promoter.enANKYLOSING SPONDYLITIS; FLAVONOID; LEI GONG TENG; NATURAL PRODUCTS; ENVIRONMENTAL PATHOGENESIS; WILFORDII HOOK-F; NF-KAPPA-B; RHEUMATOID-ARTHRITIS; NUCLEAR-FACTOR; DOUBLE-BLIND; RED-CLOVER; FLAVONOIDS; CHEMISTRY; INHIBITION; APIGENINHigh-throughput screening of chemical libraries for modulators of gene promoter activity of HLA-B2705: environmental pathogenesis and therapeutics of ankylosing spondylitisjournal article10.3899/jrheum.101109214599402-s2.0-79957864761WOS:000292534500019https://api.elsevier.com/content/abstract/scopus_id/79957864761