Shyu, Kou-GiKou-GiShyuChen, Jin-JerJin-JerChenLin, Fang-YueFang-YueLinTsai, Chang-HerChang-HerTsaiJIUNN-LEE LINTseng, Yung-ZuYung-ZuTsengLien, Wen-PinWen-PinLien2009-02-102018-07-112009-02-102018-07-111986-12http://ntur.lib.ntu.edu.tw//handle/246246/127182https://www.scopus.com/record/display.uri?eid=2-s2.0-0028081238&doi=10.1016%2f0003-4975%2894%2991656-X&origin=inward&txGid=af3c5da816f9eb9c34a44f6b74c8ecc8To evaluate the effect of mitral valve repair on the regression of left ventricular mass, we studied 50 consecutive patients with severe, pure mitral regurgitation undergoing mitral valve repair. Two-dimensional echocardiograms were recorded a mean 2.5 ± 2.0 weeks before and 6.5 ± 2.5 months after valve operation. Postoperative significant mitral regurgitation was present in 3 patients. After mitral valve repair there were significant decreases in left ventricular end-diastolic volume index (133 ± 39 mL/m2 to 79 ± 35 mL/m2; p < 0.001), end-systolic volume index (44 ± 26 mL/m2 to 30 ± 26 mL/m2; p < 0.001), stroke volume index (89 ± 29 mL/m2 to 49 ± 19 mL/m2; p < 0.001), and mass index (211 ± 82 g/m2 to 134 ± 52 g/m2; p < 0.001). There also were significant decreases in left atrial dimension (47 ± 9 mm to 38 ± 9 mm; p < 0.001), left ventricular end-diastolic dimension (61 ± 8 mm to 48 ± 7 mm; p < 0.001), and end-systolic dimension (39 ± 8 mm to 32 ± 7 mm; p < 0.001). Left ventricular ejection fraction decreased slightly from 0.69 ± 0.12 to 0.64 ± 0.12; p < 0.01) after repair. Thus, correction of pure mitral regurgitation leads to reduction of the cardiac chamber size and left ventricular volumes as well as regression of the left ventricular mass.en-USjournal article10.1016/0003-4975(94)91656-X7979733