公共衛生學系張吉仰黃致錕張郁瑩戴啟明林肇堂王榮德CHANG, CHI-YANGCHI-YANGCHANGHUANG, CHIH-KUNCHIH-KUNHUANGCHANG, YU-YINYU-YINCHANGTAI, CHI-MINGCHI-MINGTAILIN, JAW-TOWNJAW-TOWNLINWANG, JUNG-DERJUNG-DERWANG2011-05-032018-06-292011-05-032018-06-292010-10http://ntur.lib.ntu.edu.tw//handle/246246/233145BACKGROUND: The aim of this study was to evaluate the effects of Roux-en-Y gastric bypass for morbid obesity on health-related quality of life (QOL) during the first year of follow-up. METHODS: The World Health Organization Quality of Life-Brief (WHOQOL-BREF) was administered 1 month before operation, and at 1, 3, 6 and 12 months after surgery. Body mass index, co-morbidities and operation-related complications were measured at these times. A mixed-effect model was constructed to analyse repeated measurements and determine the relationships between body mass index, WHOQOL-BREF scores and other variables. RESULTS: A total of 102 patients were enrolled. The mixed-effect model showed that the physical, psychological and social domains improved after bariatric surgery, with simultaneous reduction in weight and improvement in co-morbidities. There was a dip in scores in physical and psychological domains 3-6 months after surgery, significantly related to complications. All patients gradually improved between 6 and 12 months after surgery, reaching levels similar to those of healthy subjects. CONCLUSION: Health-related QOL improved dramatically after bariatric surgery, dipped slightly between 3 and 6 months, and improved again up to the end of the first year.115871 bytesapplication/pdfen-US[SDGs]SDG3adolescent; adult; article; body mass; evaluation; female; health status; human; male; methodology; middle aged; morbid obesity; postoperative period; prospective study; quality of life; questionnaire; stomach bypass; Adolescent; Adult; Body Mass Index; Female; Gastric Bypass; Health Status; Humans; Male; Middle Aged; Obesity, Morbid; Postoperative Period; Prospective Studies; Quality of Life; Questionnaires; Young Adultjournal article10.1002/bjs.7179http://ntur.lib.ntu.edu.tw/bitstream/246246/233145/1/No.321.pdf