Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15

Hou, Chen-PangChen-PangHouTsui, Ke-HungKe-HungTsuiChang, Kang-ShuoKang-ShuoChangSung, Hsin-ChingHsin-ChingSungHsu, Shu-YuanShu-YuanHsuLin, Yu-HsiangYu-HsiangLinPEI-SHAN YANGChen, Chien-LunChien-LunChenFeng, Tsui-HsiaTsui-HsiaFengJuang, Horng-HengHorng-HengJuang2023-08-312023-08-312022-1023194170https://scholars.lib.ntu.edu.tw/handle/123456789/634822Caffeic acid phenethyl ester (CAPE), a bioactive component of propolis, has beneficial effects on cancer prevention. Growth differentiation factor 15 (GDF15) is an antitumor gene of bladder cancer. Therefore, this study investigated the anti-cancer effect of CAPE on bladder carcinoma cells and related mechanisms.enAMPK; Bladder; CAPE; GDF15; MAPK; NDRG1[SDGs]SDG3Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15journal article10.1016/j.bj.2021.10.006346627212-s2.0-85122216608https://api.elsevier.com/content/abstract/scopus_id/85122216608