Surfactin attenuates particulate matter-induced COX-2-dependent PGE2 production in human gingival fibroblasts by inhibiting TLR2 and TLR4/MyD88/NADPH oxidase/ROS/PI3K/Akt/NF-κB signaling pathway

Vo, Thi Thuy TienThi Thuy TienVoWee, YinshenYinshenWeeYUH-LIEN CHENCheng, Hsin-ChungHsin-ChungChengTuan, Vo PhuocVo PhuocTuanLee, I-TaI-TaLee2022-07-282022-07-282021-120022-3484https://scholars.lib.ntu.edu.tw/handle/123456789/615978To evaluate the anti-inflammatory effects of surfactin and underlying mechanisms against particulate matter (PM)-induced inflammatory responses in human gingival fibroblasts (HGFs).eninflammation; oral diseases; oxidative stress; particulate matter; surfactin[SDGs]SDG3[SDGs]SDG11Surfactin attenuates particulate matter-induced COX-2-dependent PGE2 production in human gingival fibroblasts by inhibiting TLR2 and TLR4/MyD88/NADPH oxidase/ROS/PI3K/Akt/NF-κB signaling pathwayjournal article10.1111/jre.12932344867572-s2.0-85114378458WOS:000692726300001https://api.elsevier.com/content/abstract/scopus_id/85114378458