內科WANG, CHENG-YICHENG-YIWANGWU, HUEY-DONGHUEY-DONGWULEE, LI-NALI-NALEE2009-09-292018-07-112009-09-292018-07-112006http://ntur.lib.ntu.edu.tw//handle/246246/93088Background: The emergence and rapid spread of multidrug- resistant isolates causing nosocomial infections, particularly pandrug-resistant Acinetobacter baumannii, pandrug-resistant Pseudomonas aeruginosa, methicillin- resistant Staphylococcus aureus, and extended-spectrum beta- lactamase- producing Enterobacteriaceae are of great concern worldwide. Methods: This study investigated the efficacy of pasteurization against contamination of culture tubes and plastic bags by the above 4 important multidrug- resistant bacteria. A 5-mL bacterial suspension with approximately 10( 5) and 10(9) cfu/mL of each organism was inoculated into 3 sets of plastic bags and culture tubes and subjected to pasteurization in a washer at 75 degrees C for 30 minutes. Results: A nearly total eradication was found after pasteurization of these 4 drug-resistant pathogens. Conclusion: Pasteurization was highly effective against drug - resistant bacteria. Strict adherence to appropriate infection control management for respiratory circuits is important for reducing the spread of drug-resistant bacteria among ventilator-assisted patients.en-USNOSOCOMIAL INFECTIONSANTIMICROBIAL RESISTANCETAIWANSURVEILLANCEDISINFECTIONjournal article