Huang, Huai-SyuanHuai-SyuanHuangLin, Yu-EnYu-EnLinPanyod, SuraphanSuraphanPanyodChen, Rou-AnRou-AnChenLin, Ying-ChengYing-ChengLinChai, Laura Min XuanLaura Min XuanChaiCHENG-CHIH HSUWEI-KAI WUKUAN-HUNG LUHuang, Yun-JuYun-JuHuangLEE-YAN SHEEN2022-12-192022-12-192023-02-1003788741https://scholars.lib.ntu.edu.tw/handle/123456789/626597Gastrodia elata Blume (GE) is a traditional Chinese dietary therapy used to treat neurological disorders. Gastrodia elata Blume water extract (WGE) has been shown to ameliorate inflammation and improve social frustration in mice in a chronic social defeat model. However, studies on the anti-depressive-like effects and cognitive impairment alleviation related to the impact of WGE on the gut microbiome of ApoE-/- mice remain elusive.enCognitive impairment; Depression; Gastrodia elata Blume water extract; Gut microbiome; Unpredictable chronic mild stress model[SDGs]SDG3Anti-depressive-like and cognitive impairment alleviation effects of Gastrodia elata Blume water extract is related to gut microbiome remodeling in ApoE-/- mice exposed to unpredictable chronic mild stressjournal article10.1016/j.jep.2022.115872363437972-s2.0-85142176575https://api.elsevier.com/content/abstract/scopus_id/85142176575