臺大公衛學院-流行病學與預防醫學研究所;Lo, Wu-ChiaWu-ChiaLoCheng, Po-WenPo-WenChengWang, Chi-TeChi-TeWangLiao, Li-JenLi-JenLiao2014-02-172018-06-292014-02-172018-06-292013http://ntur.lib.ntu.edu.tw//handle/246246/260081To determine the efficacy of real-time elastography (RTE), compared with our previously proposed prediction model, in the detection of malignancy in cervical lymph nodes (LNs). One hundred and thirty-one patients underwent ultrasound-guided fine needle aspiration biopsy (ultrasound FNAB) after ultrasound and RTE evaluation. The formula of the RTE scoring system was a four-point visual scale, based on a previously determined model. The formula of the prediction model was: . An extended model was constructed with four previous predictors and elasticity scores, using a logistic regression model. Final histology revealed 77 benign and 54 malignant LNs. In the elasticity score system, sensitivity was 66.7 %, specificity was 57.1 %, the positive predictive value (PPV) was 52.2 % and the negative predictive value (NPV) was 71.0 %. In the prediction model system, sensitivity was 79.6 %, specificity was 92.2 %, the PPV was 87.8 % and the NPV was 86.6 %. When the extended and the original model were compared, the areas under the receiver operating characteristic curve (c-statistic) was 0.94 and 0.95, respectively (P > 0.05). Qualitative RTE offers no additional value over conventional ultrasound in predicting malignancy in cervical LNs. An ultrasound system can help in the assessment of cervical lymph nodes. Grey-scale and power Doppler ultrasound remain fundamental for neck nodal evaluation. Qualitative real-time elastography provided no additional value compared with current prediction models.107 bytestext/htmlElastographyElasticity scorePrediction modelLymph nodeUltrasound10.1007/s00330-013-2861-7http://ntur.lib.ntu.edu.tw/bitstream/246246/260081/1/index.html