Shen, S.-H.S.-H.ShenTing, C.-Y.C.-Y.TingLiu, C.-Y.C.-Y.LiuCheng, H.H.ChengLiu, S.-I.S.-I.LiuCHIH-TING LINSHEN-IUAN LIU2018-09-102018-09-102014http://www.scopus.com/inward/record.url?eid=2-s2.0-84906861405&partnerID=MN8TOARShttp://scholars.lib.ntu.edu.tw/handle/123456789/386970Silicon nanowire-based biosensors have been identified as a promising biosensing technology. However, it suffers from the interface signal process to be applied into applications. In this paper, we utilize a readout circuit to directly transfer the signal obtained from a Si nanowire based sensing device into digital format. Based on the experimental results, cTnI and NT-proBNP, the biomarkers for acute myocardial infraction diagnosis, can be detected by the developed bio-sensing system in different concentration (320fM, 32pM, 3.2nM and 32nM). As a consequence, this work demonstrates the potential to translate Si nanowire biosensors device into applied bio-sensing systems. © 2014 IEEE.[SDGs]SDG16Biosensors; Crime; Sensors; Signal processing; Silicon; Acute myocardial infractions; Biosensing; Digital format; Myocardial infraction; Read-out circuit; Sensing devices; Sensing systems; Si nanowire; Nanowiresconference paper10.1109/BHI.2014.68644502-s2.0-84906861405