Neurotoxicity of a novel local anesthetic agent, ropivacaine: the possible roles of bursts of potential and cytoplasmic second messenger

PEI-LIN LINSHOU-ZEN FANTsai, Feng-FongFeng-FongTsaiTsai, Ming-ChengMing-ChengTsaiLin, Chia-HsienChia-HsienLinCHI-HSIANG HUANG2023-12-122023-12-122007-100929-6646https://scholars.lib.ntu.edu.tw/handle/123456789/637765Ropivacaine has been shown to induce convulsion following overdose or accidental intravenous injection, but the mechanisms are poorly understood. Using an identifiable central neuron from giant African snail, the authors studied the mechanism of ropivacaine-elicited bursts of potential and explored the possible mechanisms of ropivacaine-induced neurotoxicity.enCentral neuron | Convulsion | Ropivacaine | Second messenger | SnailNeurotoxicity of a novel local anesthetic agent, ropivacaine: the possible roles of bursts of potential and cytoplasmic second messengerjournal article10.1016/S0929-6646(08)60046-7179649602-s2.0-36148983057https://api.elsevier.com/content/abstract/scopus_id/36148983057