Tang QNi W.-XLeung C.-FMan W.-LLau K.K.-KLiang YLam Y.-WWong W.-YSHIE-MING PENGLiu G.-JLau T.-C.2022-12-142022-12-14201313597345https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885155074&doi=10.1039%2fc3cc42250j&partnerID=40&md5=b078d9f06dc4c5027f76ba2c5d664ed4https://scholars.lib.ntu.edu.tw/handle/123456789/626373A series of osmium(IV) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that OsVI≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs. © 2013 The Royal Society of Chemistry.[SDGs]SDG3Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Coordination Complexes; Ferric Compounds; Flow Cytometry; Hep G2 Cells; Humans; Inhibitory Concentration 50; Ligands; Molecular Structure; Osmium; antineoplastic agent; cisplatin; osmium derivative; osmium(vi)nitrido complex; quinoline derivative; quinolinolato ligand; unclassified drug; antineoplastic activity; article; cancer cell culture; controlled study; cytotoxicity; drug structure; drug synthesis; human; human cell; IC 50; in vitro studyjournal article10.1039/c3cc42250j240422702-s2.0-84885155074