CHIEN-CHANG LEETehrani, BabakBabakTehraniSHENG-NAN CHANGSOT SHIH-HUNG LIUChan, Chia-YingChia-YingChanHsu, Wan-TingWan-TingHsuHuang, Tzu-YunTzu-YunHuangPANG-SHUO HUANGJUEY-JEN HWANGCHIA-TI TSAIJIEN-JIUN CHEN2022-12-292022-12-292022-09-091945-4589https://scholars.lib.ntu.edu.tw/handle/123456789/626829Nicorandil will activate ATP-sensitive potassium channel (KATP). However, activation of potassium channels plays an important role in the mechanism of atrial fibrillation (AF) or atrial flutter (AFL). Whether use of nicorandil might contribute to initiation and/or perpetuation of AF/AFL remained unknown. We determined the relationship between use of nicorandil and risk of atrial fibrillation and determined its molecular mechanism.enatrial fibrillation; nicorandil; translational studyUse of nicorandil is associated with increased risk of incident atrial fibrillationjournal article10.18632/aging.204259360849502-s2.0-85138212981WOS:000866227100009