MING-YEN HSIAOLiao, DefeiDefeiLiaoXiang, GaomingGaomingXiangZhong, PeiPeiZhong2023-07-062023-07-062023-0503015629https://scholars.lib.ntu.edu.tw/handle/123456789/633441The ultrasound-mediated blood-brain barrier (BBB) opening with microbubbles has been widely employed, while recent studies also indicate the possibility that ultrasound alone can open the BBB through a direct mechanical effect. However, the exact mechanisms through which ultrasound interacts with the BBB and whether it can directly trigger intracellular signaling and a permeability change in the BBB endothelium remain unclear.enBlood–brain barrier; Calcium wave; Endothelial cells; Ultrasound[SDGs]SDG3journal article10.1016/j.ultrasmedbio.2022.12.019367648842-s2.0-85147689944https://api.elsevier.com/content/abstract/scopus_id/85147689944