Lai, W.W.-P.W.W.-P.LaiChuang, Y.-C.Y.-C.ChuangANGELA YU-CHEN LIN2020-02-252020-02-252017https://scholars.lib.ntu.edu.tw/handle/123456789/462696The influences of HCO3 −, Cl−, and other components on the UV/TiO2 degradation of the antineoplastic agents ifosfamide (IFO) and cyclophosphamide (CP) were studied in this work. The results indicated that the presence of HCO3 −, Cl−, NO3 −, and SO4 2− in water bodies resulted in lower degradation efficiencies. The half-lives of IFO and CP were 1.2 and 1.1 min and increased 2.3–7.3 and 3.2–6.3 times, respectively, in the presence of the four anions (initial compound concentration = 100 μg/L, TiO2 loading =100 mg/L, anion concentration = 1000 mg/L, and pH = 8). Although the presence of HCO3 − in the UV/TiO2/HCO3 − system resulted in a lower degradation rate and less byproduct formation for IFO and CP, two newly identified byproducts, P11 (M.W. = 197) and P12 (M.W. = 101), were formed and detected, suggesting that additional pathways occurred during the reaction of •CO3 − in the system. The results also showed that •CO3 − likely induces a preferred ketonization pathway. Besides the inorganic anions HCO3 −, Cl−, NO3 −, and SO4 2−, the existence of dissolved organic matter in the water has a significant effect and inhibits CP degradation. Toxicity tests showed that higher toxicity occurred in the presence of HCO3 − or Cl− during UV/TiO2 treatment and within 6 h of reaction time, implying that the effects of these two anions should not be ignored when photocatalytic treatment is applied to treat real wastewater. © 2017, Springer-Verlag Berlin Heidelberg.Bicarbonate; Carbonate radical; Chloride; Cyclophosphamide; Dissolved organic matter; Ifosfamide; TiO2 photocatalysis[SDGs]SDG3[SDGs]SDG6bicarbonate; catalysis; chloride; degradation; dissolved organic matter; drug; photolysis; pollutant removal; toxicity test; ultraviolet radiation; antineoplastic agent; bicarbonate; cyclophosphamide; ifosfamide; titanium; titanium dioxide; water; chemistry; oxidation reduction reaction; ultraviolet radiation; waste water; water management; water pollutant; Antineoplastic Agents; Bicarbonates; Cyclophosphamide; Ifosfamide; Oxidation-Reduction; Titanium; Ultraviolet Rays; Waste Water; Water; Water Pollutants, Chemical; Water Purificationjournal article10.1007/s11356-017-9005-62-s2.0-85018353463https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018353463&doi=10.1007%2fs11356-017-9005-6&partnerID=40&md5=d350aa4321ce79c7e14f6e4c14bedfb5