Shih, Hong-MouHong-MouShihSZU-YU PANWu, Chih-JenChih-JenWuChou, Yu-HsiangYu-HsiangChouChen, Chun-YuanChun-YuanChenFAN-CHI CHANGYI-TING CHENWEN-CHIH CHIANGHSING-CHEN TSAIYUNG-MING CHENSHUEI-LIONG LIN2021-11-302021-11-302021-11-0210217770https://scholars.lib.ntu.edu.tw/handle/123456789/588634Renal erythropoietin (EPO)-producing (REP) cells produce EPO through hypoxia-inducible factor (HIF) 2α-activated gene transcription. Insufficient EPO production leads to anemia in patients with chronic kidney disease. Although recombinant EPO is effective to improve anemia, no reliable REP cell lines limit further progress of research and development of novel treatment.enErythropoietin; Hypoxia-inducible factor 2α; Pericyte; Transforming growth factor-β1Transforming growth factor-β1 decreases erythropoietin production through repressing hypoxia-inducible factor 2α in erythropoietin-producing cellsjournal article10.1186/s12929-021-00770-2347249592-s2.0-85118547170https://scholars.lib.ntu.edu.tw/handle/123456789/587474