Chen, Jun-YanJun-YanChenChang, Chi-FenChi-FenChangHuang, Shu-PinShu-PinHuangCHAO-YUAN HUANGYu, Chia-ChengChia-ChengYuLin, Victor CVictor CLinGeng, Jiun-HungJiun-HungGengLi, Chia-YangChia-YangLiLu, Te-LingTe-LingLuBao, Bo-YingBo-YingBao2024-03-132024-03-132024-01-291755-8794https://scholars.lib.ntu.edu.tw/handle/123456789/640818Treatment failure following androgen deprivation therapy (ADT) presents a significant challenge in the management of advanced prostate cancer. Thus, understanding the genetic factors influencing this process could facilitate the development of personalized treatments and innovative therapeutic strategies. The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway plays a pivotal role in controlling cell growth and tumorigenesis. We hypothesized that genetic variants within this pathway may affect the clinical outcomes of patients undergoing ADT for prostate cancer.enGABRB3; Gene set enrichment analysis; PI3K/AKT pathway; Prostate cancer; Survivaljournal article10.1186/s12920-024-01816-8382873092-s2.0-85183711607https://api.elsevier.com/content/abstract/scopus_id/85183711607