HSIAO-LIN HWARUEY-JIEN CHENChen Y.C.Wang T.R.Huang S.C.SONG-NAN CHOW2020-02-032020-02-031993https://scholars.lib.ntu.edu.tw/handle/123456789/453094The optimal management of pregnant women with idiopathic thrombocytopenic purpura (ITP) is controversial. We reviewed our experience with 25 pregnancies in 19 women with ITP over a 14-year period. The incidences of bleeding during pregnancy and postpartum hemorrhage were 12.0% and 24.0%, respectively, in our series. No maternal mortality was noted. Thirteen infants were born by vaginal delivery and 12 by cesarean section. Moderate to severe neonatal thrombocytopenia (platelet count < 100 x 10(9)/L) was diagnosed in six newborns. One of them had intracranial hemorrhage complicated by a bilateral sensorineural hearing loss. ITP mothers with a prenatal platelet count < 30 x 10(9)/L and a platelet count < 100 x 10(9)/L at delivery had a higher risk of giving birth to infants with moderate to severe neonatal thrombocytopenia. Cesarean section may improve the outcome of these fetuses.[SDGs]SDG3adult; article; female; human; idiopathic thrombocytopenic purpura; newborn; pregnancy; pregnancy complication; pregnancy outcome; retrospective study; Adult; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Purpura, Thrombocytopenic, Idiopathic; Retrospective Studiesjournal article2-s2.0-0027700267