Yeh M.-H.TSEN-FANG TSAI2020-10-222020-10-2220071027-8117https://www.scopus.com/inward/record.uri?eid=2-s2.0-34250734906&partnerID=40&md5=d653eadbdfa0c92d1d88a3bbecc81ad5https://scholars.lib.ntu.edu.tw/handle/123456789/517714Psoriasis is a common chronic inflammatory skin disease that is usually managed in outpatient clinic. There is a trend to reduce hospitalization for psoriasis globally in recent years. To analyze the reasons necessitating hospitalization for psoriasis, especially the causes of acute exacerbation, a retrospective study was carried out in psoriatic inpatients admitted to National Taiwan University Hospital between April 1996 and April 2006. Available data were obtained from 120 patients. On average, there was only one psoriasis admission each month. The male to female ratio was 2.9 : 1. The mean age on admission was 45.1 years. The mean duration of hospitalization was 15.3 days. No predominant season of admission was found. Chronic plaque psoriasis was the most common clinical type in psoriatic inpatients. The duration of hospitalization was significantly associated with older age and the clinical type of psoriasis. The reasons of admission were acute exacerbation (73.3%), outpatient treatment failure (15%), uncertain initial diagnosis (10%), and nonpsoriasis-related side effects of psoriatic treatment (1.7%). The most causes of acute exacerbation were unknown (35.2%), followed by infection (29.5%), psoriatic treatment (9.1%), withdrawal of systemic steroid (5.7%), Chinese medicine (4.5%), healthy food (4.5%), topical agents (4.5%), alcohol (3.4%), medication for other concomitant diseases (2.3%), and climate (1.1%). Numerous factors are known to exacerbate psoriasis. In this study, there are some exacerbating factors of psoriasis that have not been reported before. Because this is a retrospective study, there are still a considerable percentage of patients in whom no obvious exacerbating factor is identified. Further systematic prospective researches on the basis of this study will be helpful to understand the causes and pathogenesis of psoriasis.Exacerbation; Inpatients; Psoriasis[SDGs]SDG3alcohol; Chinese drug; steroid; acute disease; adolescent; adult; aged; article; child; chronic disease; climate change; clinical study; controlled study; demography; diet therapy; disease classification; disease duration; disease exacerbation; drug withdrawal; female; hospital admission; hospitalization; human; infant; major clinical study; male; medical record; newborn; outpatient care; psoriasis; retrospective study; risk factor; skin infection; treatment failure; university hospitaljournal article2-s2.0-34250734906